SCHEMBL3873178

SCHEMBL3873178

O=C(O)COc1ccc2c(c1)C[C@@H](NC[C@H](O)c1cccc(Cl)c1)CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 19/20 1.00
ADRB1 P08588 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4640099 1.00 ADRB3 (1.00) ADRB3ADRB1
SCHEMBL3873179 1.00 ADRB3 (1.00) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4665229 0.99 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL3878377 0.99 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4639809 0.99 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4665231 0.99 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL3878376 0.99 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6133410 0.95 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6133412 0.95 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL6604673 0.95 ADRB3 (0.98) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022198259-A1 TREATMENT METHODS FOR PULMONARY ARTERIAL HYPERTENSION THE HEART RESEARCH INSTITUTE LTD (AU) 2022-09-29 WO claimed
US-20220034911-A1 METHOD OF MITIGATION OF DEATH FROM EPILEPTIC SEIZURES VEGA JOSE (US) 2022-02-03 US claimed
EP-1928448-B1 ASSOCIATION OF ß3 RECEPTOR AGONIST AND MONOAMINE REUPTAKE INHIBITORS, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC USE THEREOF SANOFI AVENTIS (FR) 2009-09-02 EP claimed
EP-1404641-B1 CRYSTALLINE FORM OF A PHENYLETHANOLAMINE, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME SANOFI AVENTIS (FR) 2008-08-06 EP claimed
US-20080182899-A1 ASSOCIATION OF BETA3 RECEPTOR AGONIST AND MONOAMINE REUPTAKE INHIBITORS, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2008-07-31 US claimed
US-6992211-B2 Crystalline form of phenylethanolamine, the preparation thereof and pharmaceutical compositions comprising the same SANOFI-AVENTIS (FR) 2006-01-31 US claimed
US-20040180953-A1 Crystalline form of phenylethanolamine, the preparation thereof and pharmaceutical compositions comprising the same SANOFI-AVENTIS (FR) 2004-09-16 US claimed
EP-0626367-B1 (7S)-7-(1R)-2-(3-chlorophenyl)-2-hydroethylamino-5,6,7,8-tetrahydronaphtalen-2-yloxy acetic acid, their pharmaceutically acceptable salts with a beta-3-adrenergic agonist activity and pharmaceutical compositions containing them SANOFI SA (FR) 1997-04-09 EP claimed
US-5488151-A {(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino)-2-hydroxyethylamino]5,} acetic acid and its pharmaceutically acceptable salts SANOFI (FR) 1996-01-30 US claimed
JP-7070013-A None JP disclosed
JP-7070013-A None JP disclosed
EP-4638496-A1 SELECTIVE AND POTENT INHIBITORY ANTIBODIES OF MYOSTATIN ACTIVATION Scholar Rock, Inc. (US) 2025-10-29 EP disclosed
US-12312599-B2 Methods, compositions, and kits for producing beige adipocytes and treating metabolic disorders MaineHealth (US) 2025-05-27 US disclosed
EP-4525833-A2 VETERINARY PHARMACEUTICAL FORMULATIONS Increvet, Inc. (US) 2025-03-26 EP disclosed
US-5488151-A {(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino)-2-hydroxyethylamino]5,} acetic acid and its pharmaceutically acceptable salts SANOFI (FR) 1996-01-30 US disclosed
US-5488151-A {(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino)-2-hydroxyethylamino]5,} acetic acid and its pharmaceutically acceptable salts SANOFI (FR) 1996-01-30 US disclosed
JP-H0770013-A ((7S)-7-((2R)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYLAMINO)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YLOXY)ACETIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALT ACTING AS BETA 3-ADRENERGIC AGONISTS, PHARMACEUTICAL COMPOSITION AND LABORATORY REAGENT IN WHICH IT IS PRESENT SANOFI SA 1995-03-14 JP disclosed
JP-H0770013-A ((7S)-7-((2R)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYLAMINO)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YLOXY)ACETIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALT ACTING AS BETA 3-ADRENERGIC AGONISTS, PHARMACEUTICAL COMPOSITION AND LABORATORY REAGENT IN WHICH IT IS PRESENT SANOFI SA 1995-03-14 JP disclosed
EP-0627407-A1 (7S)-7-(2(3-chlorophenyl)-2-hydroethylamino-5,6,7,8-tetrahydro-naphthalen-2-yloxy acetic acid, their pharmaceutically acceptable salts with a beta-3-adrenergic agonist activity and pharmaceutical compositions containing them MIDY S.p.A. (IT) 1994-12-07 EP disclosed
EP-0626367-A1 (7S)-7-(1R)-2-(3-chlorophenyl)-2-hydroethylamino-5,6,7,8-tetrahydronaphtalen-2-yloxy acetic acid, their pharmaceutically acceptable salts with a beta-3-adrenergic agonist activity and pharmaceutical compositions containing them SANOFI (FR) 1994-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182899-A1 ASSOCIATION OF BETA3 RECEPTOR AGONIST AND MONOAMINE REUPTAKE INHIBITORS, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC USE THEREOF ADRB3, ADRB1, ADRB2 ADRB3 1/4885ADRB1 2/4885
US-12312599-B2 Methods, compositions, and kits for producing beige adipocytes and treating metabolic disorders FABP4, LIPC, PNLIP ADRB3 1065/4885ADRB1 1677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.