SCHEMBL1666632

SCHEMBL1666632

NN[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 7/20 0.36
CPB1 P15086 1/20 0.36
GNPAT O15228 2/20 0.32
CYP3A4 P08684 1/20 0.31
SLC7A5 Q01650 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666636 1.00 CPB2 (0.36) CPB2CPB1GNPATCYP3A4SLC7A5
SCHEMBL1331492 1.00 CPB2 (0.36) CPB2CPB1GNPATCYP3A4SLC7A5
SCHEMBL3501671 0.90 CPB2 (0.34) CPB2CPB1
SCHEMBL8526486 0.88 CPB2 (0.34) CPB2CPB1
SCHEMBL8526485 0.88 CPB2 (0.34) CPB2CPB1
SCHEMBL13267780 0.87
SCHEMBL3378642 0.85 CPB2 (0.34) CPB2CPB1SMN1; SMN2
Hydrochloric Acid SCHEMBL30634622 0.85 CPB2 (0.34) CPB2CPB1SMN1; SMN2
SCHEMBL3378638 0.85 CPB2 (0.34) CPB2CPB1SMN1; SMN2
SCHEMBL669445 0.85 CPB2 (0.34) CPB2CPB1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248037-A1 FLAVOUR ADDITIVES MARS, INCORPORATED (US) 2023-08-10 US claimed
CN-100374153-C Use of GLP-1 or analogs in treatment of myocardial infraction LILLY CO ELI (US) 2008-03-12 CN claimed
CN-101005857-A Polypeptide protracting tags NOVO NORDISK AS (DK) 2007-07-25 CN claimed
CN-1268391-C Use of GLP-1 analogs and derivatives administered peripherally in regulation of obesity LILLY CO ELI (US) 2006-08-09 CN claimed
EP-1664108-A1 SEPARATION OF POLYPEPTIDES COMPRISING A RACEMIZED AMINO ACID NOVO NORDISK A/S (DK) 2006-06-07 EP claimed
WO-2005019261-A1 SEPARATION OF POLYPEPTIDES COMPRISING A RACEMIZED AMINO ACID NOVO NORDISK A/S (DK) 2005-03-03 WO claimed
EP-1355942-A2 GLP-1 FUSION PROTEINS ELI LILLY AND COMPANY (US) 2003-10-29 EP claimed
WO-2002046227-A2 GLP-1 FUSION PROTEINS ELI LILLY AND COMPANY (US) 2002-06-13 WO claimed
CN-117820232-A Non-covalent dimer cations, salts thereof, preparation method thereof and antioxidation application thereof 苏州质子链生物技术有限公司 2024-04-05 CN disclosed
CN-115103719-A Encapsulated fragrance based on natural amino acids 西姆莱斯股份公司 2022-09-23 CN disclosed
EP-4007493-A1 STABLE AQUEOUS MICROBIAL COMPOSITION Biowish Technologies, Inc. (US) 2022-06-08 EP disclosed
WO-2021022128-A1 STABLE AQUEOUS MICROBIAL COMPOSITION BiOWiSH Technologies, Inc. (US) 2021-02-04 WO disclosed
EP-3033112-A1 GLP-1 DERIVATIVES, AND USES THEREOF Novo Nordisk A/S (DK) 2016-06-22 EP disclosed
EP-3016975-A1 DERIVATIVES OF GLP-1 LIKE PEPTIDES, AND USES THEREOF Novo Nordisk A/S (DK) 2016-05-11 EP disclosed
EP-1287147-A2 IMMUNOTOXIN FUSION PROTEINS AND MEANS FOR EXPRESSION THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2003-03-05 EP disclosed
WO-2001087982-A2 IMMUNOTOXIN FUSION PROTEINS AND MEANS FOR EXPRESSION THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-11-22 WO disclosed
CN-1322137-A Use of GLP-1 or analogs in the treatment of stroke LILLY CO ELI (US) 2001-11-14 CN disclosed
CN-1281369-A Glucagon-like peptide-1 crystals LILLY CO ELI (US) 2001-01-24 CN disclosed
CN-1242707-A Use of GLP-1 analogs and derivatives administered peripherally in regulation of obesity LILLY CO ELI (US) 2000-01-26 CN disclosed
CN-1235553-A Use of GLP-1 or analogs in treatment of myocardial infraction LILLY CO ELI (US) 1999-11-17 CN disclosed