SCHEMBL8526486

SCHEMBL8526486

NNN[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 7/20 0.34
CPB1 P15086 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526485 1.00 CPB2 (0.34) CPB2CPB1
Hydrochloric Acid SCHEMBL30634622 0.89 CPB2 (0.34) CPB2CPB1
SCHEMBL1331492 0.88 CPB2 (0.36) CPB2CPB1
SCHEMBL1666636 0.88 CPB2 (0.36) CPB2CPB1
SCHEMBL1666632 0.88 CPB2 (0.36) CPB2CPB1
SCHEMBL29867821 0.85 CPB2 (0.33) CPB2CPB1
SCHEMBL31146592 0.85 MME (0.34) CPB2CPB1
SCHEMBL29693301 0.84 KDM4E (0.34) CPB2CPB1
SCHEMBL11855224 0.83 CPB2 (0.32) CPB2CPB1
SCHEMBL11855203 0.83 CPB2 (0.32) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688209-A1 GLYCOSYLATION OF LIPIDS AND LIPID-CONTAINING PARTICLES, AND DIAGNOSTIC AND THERAPEUTIC METHODS AND MATERIALS DERIVED THEREFROM THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1995-12-27 EP claimed
WO-1994020083-A1 GLYCOSYLATION OF LIPIDS AND LIPID-CONTAINING PARTICLES, AND DIAGNOSTIC AND THERAPEUTIC METHODS AND MATERIALS DERIVED THEREFROM THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1994-09-15 WO claimed
EP-0327919-A2 Method and agents for preventing staining of teeth THE ROCKEFELLER UNIVERSITY (US) 1989-08-16 EP claimed
EP-0827511-A1 AGENTS FOR BINDING TO ADVANCED GLYCOSYLATION ENDPRODUCTS, AND METHODS OF THEIR USE THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1998-03-11 EP disclosed
WO-1996031537-A9 AGENTS FOR BINDING TO ADVANCED GLYCOSYLATION ENDPRODUCTS, AND METHODS OF THEIR USE 1996-12-27 WO disclosed
WO-1996031537-A1 AGENTS FOR BINDING TO ADVANCED GLYCOSYLATION ENDPRODUCTS, AND METHODS OF THEIR USE THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1996-10-10 WO disclosed
EP-0688209-A1 GLYCOSYLATION OF LIPIDS AND LIPID-CONTAINING PARTICLES, AND DIAGNOSTIC AND THERAPEUTIC METHODS AND MATERIALS DERIVED THEREFROM THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1995-12-27 EP disclosed
WO-1995029692-A1 AN ADVANCED GLYCOSYLATION ENDPRODUCT-RECEPTOR, AND DIAGNOSTIC AND THERAPEUTIC METHODS BASED THEREON THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1995-11-09 WO disclosed
EP-0624088-A1 AMINO ACIDS USEFUL AS INHIBITORS OF THE ADVANCED GLYCOSYLATION OF PROTEINS THE ROCKEFELLER UNIVERSITY (US) 1994-11-17 EP disclosed
WO-1994020083-A1 GLYCOSYLATION OF LIPIDS AND LIPID-CONTAINING PARTICLES, AND DIAGNOSTIC AND THERAPEUTIC METHODS AND MATERIALS DERIVED THEREFROM THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1994-09-15 WO disclosed
US-5338757-A Administering antihistamines THE PENN STATE RESEARCH FOUNDATION (US) 1994-08-16 US disclosed
WO-1993014750-A2 AMINO ACIDS USEFUL AS INHIBITORS OF THE ADVANCED GLYCOSYLATION OF PROTEINS THE ROCKEFELLER UNIVERSITY (US) 1993-08-05 WO disclosed
EP-0433679-A2 Pharmaceutical compositions for inhibition of maillard's reaction Senju Pharmaceutical Co., Ltd. (JP) 1991-06-26 EP disclosed
EP-0430045-A2 Ascorbic acid tocopheryl phosphate diesters for inhibition of Maillard's reaction Senju Pharmaceutical Co., Ltd. (JP) 1991-06-05 EP disclosed
US-5019591-A Antihistamines PENNSYLVANIA RESEARCH CORPORATION (US) 1991-05-28 US disclosed
EP-0316852-A2 Inhibitors of nonenzymatic cross-linking THE ROCKEFELLER UNIVERSITY (US) 1989-05-24 EP disclosed
US-4758583-A Method and agents for inhibiting protein aging THE ROCKEFELLER UNIVERSITY (US) 1988-07-19 US disclosed
EP-0222313-A2 Method and agents for inhibiting protein aging THE ROCKEFELLER UNIVERSITY (US) 1987-05-20 EP disclosed