SCHEMBL16666393

SCHEMBL16666393

O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)SCCOC(=O)c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ UBASH3B Q8TF42 1/20 0.68
▸ TACR1 P25103 7/20 0.49
▸ F11 P03951 2/20 0.45
▸ MAPT P10636 1/20 0.43
▸ PPARG P37231 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ CCKBR P32239 1/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16676584 0.89 UBASH3B (0.72) UBASH3BTACR1F11MAPTPPARG
SCHEMBL16676557 0.87 UBASH3B (0.72) UBASH3BTACR1F11MAPTPPARG
SCHEMBL29868847 0.87 UBASH3B (0.74) UBASH3BTACR1F11MAPTPPARG
SCHEMBL16666864 0.87 UBASH3B (0.74) UBASH3BTACR1F11MAPTPPARG
SCHEMBL16676563 0.86 UBASH3B (0.72) UBASH3BTACR1F11PPARGKDM4E
SCHEMBL29868810 0.86 UBASH3B (0.72) UBASH3BTACR1F11PPARGKDM4E
SCHEMBL16667576 0.85 UBASH3B (0.71) UBASH3BTACR1F11PPARGKDM4E
SCHEMBL16666706 0.85 UBASH3B (0.68) UBASH3BTACR1F11MAPTPPARG
SCHEMBL23280196 0.84 UBASH3B (0.70) UBASH3BTACR1F11PPARGKDM4E
SCHEMBL16666374 0.84 UBASH3B (0.70) UBASH3BTACR1F11PPARGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150141409-A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF ASTECH. CO., LTD. (KR) 2015-05-21 — — US claimed
EP-2865669-A1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF Samjin Pharmaceutical Co., Ltd. (KR) 2015-04-29 — — EP claimed
EP-2865669-B1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF SAMJIN PHARM CO LTD (KR) 2021-04-28 — — EP disclosed
EP-2865669-B1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF SAMJIN PHARM CO LTD (KR) 2021-04-28 — — EP disclosed
US-20150141409-A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF ASTECH. CO., LTD. (KR) 2015-05-21 — — US disclosed
US-20150141409-A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF ASTECH. CO., LTD. (KR) 2015-05-21 — — US disclosed
US-20150141409-A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF ASTECH. CO., LTD. (KR) 2015-05-21 — — US disclosed
EP-2865669-A1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF Samjin Pharmaceutical Co., Ltd. (KR) 2015-04-29 — — EP disclosed
EP-2865669-A1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF Samjin Pharmaceutical Co., Ltd. (KR) 2015-04-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141409-A1 NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF REV1, GRPR, SI UBASH3B 2690/4885TACR1 2155/4885F11 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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