Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.47 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748750 | 0.88 | CYP3A4 (0.49) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL18676462 | 0.87 | ITGB2 (0.64) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL23387015 | 0.85 | HRH3 (0.47) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL23513624 | 0.85 | HTR1D (0.48) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL9924208 | 0.85 | CYP3A4 (0.53) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL10339074 | 0.85 | SLC6A5 (0.60) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL27043238 | 0.84 | ITGB2 (0.60) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL151336 | 0.84 | ITGB2 (0.60) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL163397 | 0.84 | ITGB2 (0.60) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 | |
| SCHEMBL1667031 | 0.84 | SLC6A5 (0.62) | ALDH1A1CYP3A4CYP1A2CYP2C19ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490709-B1 | PEPTIDIC GLP-2 AGONISTS | FERRING BV (NL) | 2014-11-26 | — | — | EP | disclosed |
| US-8580918-B2 | Peptidic GLP-2 agonists | FERRING B.V. (NL) | 2013-11-12 | — | — | US | disclosed |
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | FERRING B.V. (NL) | 2012-09-13 | — | — | US | disclosed |
| EP-2314616-A1 | Peptidic GLP-2 agonists | Ferring B.V. (NL) | 2011-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | GLP1R, GIPR, IAPP | ALDH1A1 4333/4885CYP3A4 3128/4885CYP1A2 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.