Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 13/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19272381 | 0.90 | S1PR5 (0.60) | ENPP2S1PR5 | |
| SCHEMBL11942515 | 0.90 | S1PR5 (0.60) | ENPP2S1PR5 | |
| SCHEMBL1161489 | 0.90 | S1PR5 (0.60) | ENPP2S1PR5 | |
| SCHEMBL16667001 | 0.88 | ENPP2 (0.53) | ENPP2S1PR5 | |
| SCHEMBL11027735 | 0.86 | ENPP2 (0.50) | ENPP2S1PR5 | |
| SCHEMBL18532957 | 0.86 | ENPP2 (0.50) | ENPP2S1PR5 | |
| SCHEMBL11942516 | 0.86 | ENPP2 (0.50) | ENPP2S1PR5 | |
| SCHEMBL1161329 | 0.85 | S1PR5 (0.62) | ENPP2S1PR5 | |
| SCHEMBL11942519 | 0.85 | S1PR5 (0.62) | ENPP2S1PR5 | |
| SCHEMBL15922567 | 0.85 | S1PR5 (0.62) | ENPP2S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461683-B1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | BIOGEN IDEC INC (US) | 2015-04-29 | — | — | EP | claimed |