Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480383 | 0.91 | MAP3K5 (0.32) | MAP3K5MCL1MAPT | |
| SCHEMBL16684162 | 0.87 | MAP3K5 (0.40) | MAP3K5MCL1MAPT | |
| SCHEMBL16667390 | 0.84 | MAP3K5 (0.41) | MAP3K5MCL1MAPT | |
| SCHEMBL3919835 | 0.81 | MCL1 (0.36) | MAP3K5MCL1MAPT | |
| SCHEMBL16667405 | 0.80 | P2RY14 (0.38) | MAP3K5MAPT | |
| SCHEMBL3480413 | 0.75 | MAP3K5 (0.35) | MAP3K5MCL1MAPT | |
| SCHEMBL13032461 | 0.75 | ADRA1A (0.34) | MAPT | |
| SCHEMBL3483815 | 0.75 | MCL1 (0.32) | MAP3K5MCL1MAPT | |
| Trifluoroacetic Acid SCHEMBL3480361 | 0.73 | S1PR1 (0.31) | — | |
| SCHEMBL13021136 | 0.73 | EGLN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-B1 | NOVEL INHIBITORS OF BETA-LACTAMASE | METHYLGENE INC (CA) | 2015-04-29 | — | — | EP | claimed |