Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668179 | 0.90 | HDAC1 (0.55) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16667802 | 0.79 | POLB (1.00) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16668021 | 0.78 | HDAC1 (0.67) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16667740 | 0.78 | POLB (0.71) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16674525 | 0.75 | TSHR (0.73) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL24031073 | 0.74 | HDAC6 (1.00) | TP53HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL24031096 | 0.73 | HDAC1 (0.76) | TP53HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL10487897 | 0.73 | TSHR (0.62) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16667845 | 0.71 | POLB (0.85) | POLBALDH1A1TP53MAPTHDAC1 | |
| SCHEMBL16668018 | 0.70 | POLB (0.84) | POLBALDH1A1TP53MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854780-B1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIV KANSAS (US) | 2017-08-30 | — | — | EP | claimed |
| US-9499496-B2 | Inhibitors of respiratory syncytial virus | UNIVERSITY OF KANSAS (US) | 2016-11-22 | — | — | US | claimed |
| US-20150119411-A1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIVERSITY OF KANSAS | 2015-04-30 | — | — | US | claimed |
| EP-2854780-B1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIV KANSAS (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2854780-B1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIV KANSAS (US) | 2017-08-30 | — | — | EP | disclosed |
| US-9499496-B2 | Inhibitors of respiratory syncytial virus | UNIVERSITY OF KANSAS (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499496-B2 | Inhibitors of respiratory syncytial virus | UNIVERSITY OF KANSAS (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499496-B2 | Inhibitors of respiratory syncytial virus | UNIVERSITY OF KANSAS (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150119411-A1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIVERSITY OF KANSAS | 2015-04-30 | — | — | US | disclosed |
| US-20150119411-A1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIVERSITY OF KANSAS | 2015-04-30 | — | — | US | disclosed |
| US-20150119411-A1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | UNIVERSITY OF KANSAS | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119411-A1 | INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS | SARS1, MAVS, RNASEH1 | POLB 230/4885ALDH1A1 4186/4885TP53 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.