SCHEMBL166690

SCHEMBL166690

Cc1ccc(C(C)(C)C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 1.00
NPC1 O15118 2/20 0.58
MAPT P10636 2/20 0.58
RAB9A P51151 2/20 0.58
LMNA P02545 2/20 0.55
TYR P14679 1/20 0.55
ACHE P22303 4/20 0.53
TDP1 Q9NUW8 2/20 0.53
BCHE P06276 2/20 0.47
KIF11 P52732 2/20 0.46
ALDH1A1 P00352 4/20 0.44
HSD11B1 P28845 1/20 0.43
HPGD P15428 2/20 0.42
MAPK1 P28482 1/20 0.42
HDAC1 Q13547 1/20 0.42
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5495871 1.00 TSHR (1.00) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL24522303 0.91 TSHR (0.83) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL19192713 0.91 TSHR (0.83) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL24599236 0.91 TSHR (0.83) TSHRNPC1MAPTRAB9ALMNA
Ethane SCHEMBL28803106 0.89 TSHR (0.79) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL2793711 0.89 TSHR (0.79) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL24129902 0.87 TSHR (0.75) TSHRNPC1MAPTRAB9ALMNA
P-Cresol SCHEMBL8761754 0.87 LMNA (0.80) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL424728 0.86 TSHR (0.73) TSHRNPC1MAPTRAB9ALMNA
SCHEMBL24703484 0.84 TSHR (0.71) TSHRNPC1MAPTRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3402 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441964-B2 Cleaning agent composition and cleaning method NISSAN CHEMICAL CORPORATION (JP) 2025-10-14 US claimed
EP-4584277-A1 BIS (ARENE) METAL COMPLEXES AND RELATED METHODS Entegris, Inc. (US) 2025-07-16 EP claimed
US-12337304-B2 Palladium-containing composition and hydrogen peroxide production method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-06-24 US claimed
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-119954987-A Apoptosis bionic nano drug delivery carrier and preparation method and application thereof 暨南大学 2025-05-09 CN claimed
CN-119968378-A Bis (aromatic hydrocarbon) metal complexes and related methods 恩特格里斯公司 2025-05-09 CN claimed
CN-119874471-A Preparation method and application of p-tert-butyltoluene 中国石油化工股份有限公司 2025-04-25 CN claimed
CN-119751238-A Preparation method of p-tert-butylbenzoic acid and p-tert-butylbenzoic acid 江西永通科技股份有限公司 2025-04-04 CN claimed
CN-119661431-A Synthesis method of 3-hydroxyquinoline derivative 常州大学 2025-03-21 CN claimed
US-4255356-A Purification of tertiary amines using an adsorbent CHEMISCHE WERKE HULS AG (DE) 1981-03-10 US claimed
US-4235683-A Electrolytic preparation of benzaldehydes BASF AKTIENGESELLSCHAFT (DE) 1980-11-25 US claimed
US-4212711-A Electrochemical oxidation of alkyl aromatic compounds UOP INC. (US) 1980-07-15 US claimed
EP-0012942-A2 Electrolytic process for producing benzaldehydes BASF Aktiengesellschaft (DE) 1980-07-09 EP claimed
EP-0012570-A2 Selective reaction of 1,4-disubstituted benzene compounds MOBIL OIL CORPORATION (US) 1980-06-25 EP claimed
EP-0011288-A1 p-Tert.-butylbenzotribromide and his derivatives which are substituted in the ring by halogen, a process for their preparation as well as their use. HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-28 EP claimed
EP-0011281-A2 Process for the preparation of p-tert.-butyl benzaldehyde and the derivatives thereof substituted in the nucleus by halogen. HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-28 EP claimed
US-4181811-A USING A CRYSTALLINE ALUMINA-SILICA ZEOLITE CATALYST TO PRODUCE 1,2 OR 1,3-ISOMERS MOBIL OIL CORPORATION (US) 1980-01-01 US claimed
US-4177288-A FUNGICIDES, COPPER SALTS AND SURFACTANTS WITH HALOGENATED BENZONITRILES CITIES SERVICE COMPANY (US) 1979-12-04 US claimed
US-4148696-A Electrochemical oxidation of activated alkyl aromatic compounds UOP INC. (US) 1979-04-10 US claimed