Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1501532 | 1.00 | CA1 (0.50) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL16669322 | 0.97 | CA1 (0.47) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL4395305 | 0.94 | CA1 (0.44) | CA1CA4FAHD1 | |
| Acetic Acid SCHEMBL1678845 | 0.94 | CA1 (0.44) | CA1CA4FAHD1 | |
| Acetic Acid SCHEMBL27895513 | 0.91 | CA2 (0.46) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL27969590 | 0.87 | CA2 (0.48) | CA1CA4MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL29148901 | 0.86 | FFAR3 (0.41) | CA1CA4MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL28193583 | 0.86 | FFAR3 (0.41) | CA1CA4MEN1KMT2AALDH1A1 | |
| Bicarbonate SCHEMBL8405677 | 0.86 | CA4 (0.39) | CA1CA4FAHD1MEN1KMT2A | |
| Acetic Acid SCHEMBL28569287 | 0.82 | CA2 (0.48) | CA1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290265-A | Monomer compound and preparation method thereof, polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117801175-A | Low-sensitivity ester polycarboxylate water reducer and preparation method and application thereof | 科之杰新材料集团有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117777375-A | Ether polycarboxylate water reducer and preparation method and application thereof | 科之杰新材料集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720691-A | Ether polycarboxylic acid slump retaining agent and preparation method and application thereof | 陕西科之杰新材料有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117700640-A | Low-sensitivity ester polycarboxylic acid slump retaining agent and preparation method and application thereof | 陕西科之杰新材料有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-115785545-B | Rubber composition and vulcanized rubber | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117402291-A | Modified diene polymer, preparation method and application thereof and rubber composition | 中国石油化工股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117384327-A | Gypsum water reducer and preparation method and application thereof | 科之杰新材料集团福建有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117343244-A | Gypsum water reducer with small flow loss with time as well as preparation method and application thereof | 科之杰新材料集团福建有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117264102-A | Liquid rubber and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-108299697-B | Rubber, preparation method thereof, rubber composition and vulcanized rubber | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-108003983-B | Lubricating oil composition for diesel engine and preparation method thereof | 中国石油化工股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-108003980-B | Gasoline engine lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-108003981-B | Gasoline engine lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110938026-A | Monomer compound and preparation method thereof, copolymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-107540783-B | Acrylate polymer and application thereof, and lubricating oil pour point depressant and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-108003982-B | Lubricating oil composition for diesel engine and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-108003971-B | Lubricating oil composition and method for improving low-temperature performance of lubricating oil | 中国石油化工股份有限公司 | 2020-02-28 | — | — | CN | disclosed |
| US-9296840-B2 | Functional diene polymer, preparation method thereof, and rubber composition comprising the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-03-29 | — | — | US | disclosed |
| US-20150119528-A1 | FUNCTIONAL DIENE POLYMER, PREPARATION METHOD THEREOF, AND RUBBER COMPOSITION COMPRISING THE SAME | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2015-04-30 | — | — | US | disclosed |