Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27929686 | 0.90 | CA2 (0.48) | CA4FAHD1MEN1KMT2AALDH1A1 | |
| Bicarbonate SCHEMBL5471125 | 0.88 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRCA1 | |
| Hydrogen Peroxide SCHEMBL5165096 | 0.87 | MEN1 (0.38) | MEN1KMT2AALDH1A1TSHR | |
| Hydrogen Peroxide SCHEMBL2572903 | 0.87 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHR | |
| Hydrogen Peroxide SCHEMBL3145484 | 0.87 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHR | |
| Hydrogen Peroxide SCHEMBL6158835 | 0.87 | MEN1 (0.38) | MEN1KMT2AALDH1A1TSHR | |
| Acetic Acid SCHEMBL1501532 | 0.86 | CA1 (0.50) | CA4FAHD1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL16669154 | 0.86 | CA1 (0.50) | CA4FAHD1MEN1KMT2AALDH1A1 | |
| Bicarbonate SCHEMBL30978282 | 0.85 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHRCA1 | |
| Oxalic Acid SCHEMBL27870285 | 0.85 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702036-B1 | FLUOROCOPOLYMER, PROCESS FOR PRODUCING THE SAME, AND FLUOROELASTOMER | DAIKIN IND LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5650472-A | RADICAL COPOLYMERIZATION OF ETHYLENE, HEXAFLUOROPROPYLENE AND TETRAFLUOROETHYLENE | DAIKIN INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0702036-A1 | FLUOROCOPOLYMER, PROCESS FOR PRODUCING THE SAME, AND FLUOROELASTOMER | DAIKIN INDUSTRIES, LIMITED (JP) | 1996-03-20 | — | — | EP | disclosed |