Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL16669263

Cc1cccc([B-](c2cccc(C)c2)(c2cccc(C)c2)c2cccc(C)c2)c1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.41
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
HPGD P15428 1/20 0.37
ACP3 P15309 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
EPHX1 P07099 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1452514 0.83 ACHE (0.58) ACHENPSR1TSHRLMNAALOX12
SCHEMBL134691 0.81 ACHE (0.55) ACHENPSR1TSHRLMNAALOX12
Potassium Ion SCHEMBL135397 0.81 ACHE (0.55) ACHENPSR1TSHRLMNAALOX12
Ammonia Solution, Strong SCHEMBL6065927 0.81 ACHE (0.55) ACHENPSR1TSHRLMNAALOX12
SCHEMBL4961104 0.81 ACHE (0.55) ACHENPSR1TSHRLMNAALOX12
Lithium Ion SCHEMBL132932 0.81 ACHE (0.55) ACHENPSR1TSHRLMNAALOX12
SCHEMBL6913511 0.81 ACHE (0.41) ACHENPSR1TSHRLMNAALOX12
Tetraphenylphosphonium SCHEMBL23455574 0.80 TSHR (0.40) ACHENPSR1TSHRLMNAALOX12
Bromide SCHEMBL7886077 0.79 ACHE (0.48) ACHENPSR1TSHRLMNAALOX12
Tetraphenylphosphonium SCHEMBL15070 0.79 HIF1A (0.38) SMN1; SMN2HPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983162-B2 Method and device for detection of bioavailable drug concentration THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-05-29 US claimed
US-20150119848-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2015-04-30 US claimed
EP-3629928-B1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIV OF TENNESSEE RESEARCH FOUNDATION (US) 2025-11-05 EP disclosed
US-11686722-B2 Compositions and methods to detect molecules in a sample INFUSENSE CORP. (US) 2023-06-27 US disclosed
US-11375929-B2 Method and device for detection of bioavailable drug concentration in a fluid sample THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2022-07-05 US disclosed
EP-3629928-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE The University of Tennessee Research Foundation (US) 2020-04-08 EP disclosed
US-20190331656-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. 2019-10-31 US disclosed
EP-3555609-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE Infusense Corp. (US) 2019-10-23 EP disclosed
WO-2018222820-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-12-06 WO disclosed
US-20180271413-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2018-09-27 US disclosed
WO-2018112458-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. (US) 2018-06-21 WO disclosed
US-9983162-B2 Method and device for detection of bioavailable drug concentration THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-05-29 US disclosed
US-20150119848-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2015-04-30 US disclosed