Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452514 | 0.97 | ACHE (0.58) | ACHEALDH1A1MAPK1TP53TDP1 | |
| Potassium Ion SCHEMBL135397 | 0.95 | ACHE (0.55) | ACHEALDH1A1MAPK1TP53TDP1 | |
| Lithium Ion SCHEMBL132932 | 0.95 | ACHE (0.55) | ACHEALDH1A1MAPK1TP53TDP1 | |
| Ammonia Solution, Strong SCHEMBL6065927 | 0.95 | ACHE (0.55) | ACHEALDH1A1MAPK1TP53TDP1 | |
| SCHEMBL4961104 | 0.95 | ACHE (0.55) | ACHEALDH1A1MAPK1TP53TDP1 | |
| Hexane SCHEMBL31304731 | 0.84 | ACHE (0.44) | ACHEALDH1A1MAPK1TP53NPC1 | |
| SCHEMBL17707707 | 0.84 | ACHE (0.39) | ACHEALDH1A1MAPK1TP53TDP1 | |
| SCHEMBL134402 | 0.83 | ACHE (0.42) | ACHEALDH1A1MAPK1TP53TDP1 | |
| SCHEMBL30960192 | 0.83 | ACHE (0.42) | ACHEALDH1A1MAPK1TP53TDP1 | |
| SCHEMBL6913511 | 0.81 | ACHE (0.41) | ACHEALDH1A1MAPK1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239190-A2 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING | Chevron Phillips Chemical Company LP (US) | 2017-11-01 | — | — | EP | claimed |
| EP-2235069-B1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-11-25 | — | — | EP | claimed |
| EP-2231717-B1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-10-21 | — | — | EP | claimed |
| EP-2231716-B1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2014-04-16 | — | — | EP | claimed |
| US-8524626-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-09-03 | — | — | US | claimed |
| US-8329833-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-12-11 | — | — | US | claimed |
| US-20120149855-A1 | Nano-Linked Metallocene Catalyst Compositions and Their Polymer Products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-06-14 | — | — | US | claimed |
| US-8143183-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-27 | — | — | US | claimed |
| US-20120058886-A1 | Nano-Linked Metallocene Catalyst Compositions and Their Polymer Products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-08 | — | — | US | claimed |
| US-8012900-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) | 2011-09-06 | — | — | US | claimed |
| WO-2005068519-A2 | CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2005-07-28 | — | — | WO | claimed |
| US-20050159300-A1 | Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-07-21 | — | — | US | claimed |
| US-20050153830-A1 | contact product of a first metallocene compound, a second metallocene compound, a chemically-treated solid oxide, and an organoaluminum compound; useful properties in impact, tear, adhesion, sealing, extruder motor loads and pressures at comparable melt index values, and neck-in and draw-down. | CHEVRON PHILIPS CHEMICAL COMPANY LP | 2005-07-14 | — | — | US | claimed |
| WO-2005052011-A1 | CATALYST COMPOSITIONS FOR PRODUCING POLYOLEFINS IN THE ABSENCE OF COCATALYSTS | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2005-06-09 | — | — | WO | claimed |
| US-20050113245-A1 | STANNOXY-SUBSTITUTED METALLOCENE CATALYSTS FOR OLEFIN AND ACETYLENE POLYMERIZATION | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-05-26 | — | — | US | claimed |
| US-20050113243-A1 | Catalyst compositions for producing polyolefins in the absence of cocatalysts | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2005-05-26 | — | — | US | claimed |
| EP-0548826-B1 | Diallyl ammonium-compounds, method for their preparation and their application | HOECHST AG (DE) | 1997-04-23 | — | — | EP | claimed |
| EP-0476648-B1 | Polymeric ammonium borates and process for their preparation | HOECHST AG (DE) | 1995-06-21 | — | — | EP | claimed |
| EP-0507824-B1 | BISCATIONIC ACID AMIDE AND ACID IMIDE DERIVATIVES AND PROCESS FOR PREPARING THEM | HOECHST AG (DE) | 1994-10-19 | — | — | EP | claimed |
| US-5329046-A | Compounds with boron anions for charge control toners and developers for electrographic recording and charge controllers | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | claimed |