Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20543243 | 0.85 | MEN1 (0.36) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL29375118 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL29493741 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL16176940 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL16177483 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL29756627 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL29615782 | 0.83 | PDK2 (0.55) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL16670301 | 0.81 | PDK2 (0.47) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL18466672 | 0.78 | PDK2 (0.43) | PDK2ESR1ESR2SMN1; SMN2KDM4E | |
| SCHEMBL2233600 | 0.78 | MEN1 (0.47) | PDK2ESR1ESR2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |