SCHEMBL2233600

SCHEMBL2233600

Cc1ccc(C2(c3ccc(C)cc3)c3c[c]ccc3-c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
OPRK1 P41145 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
KIF11 P52732 1/20 0.37
POLB P06746 1/20 0.35
PDK2 Q15119 3/20 0.33
OPRM1 P35372 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
PGR P06401 1/20 0.31
MDM2 Q00987 1/20 0.31
HKDC1 Q2TB90 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL827868 0.86 MEN1 (0.48) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL8984601 0.84 MEN1 (0.63) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL30009193 0.84 MEN1 (0.63) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL991993 0.82 KDM4E (0.41) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3741162 0.82 KDM4E (0.41) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL7707020 0.82 KDM4E (0.41) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL1715623 0.81 LMNA (0.39) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL19312967 0.81 LMNA (0.59) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL2408628 0.78 LMNA (0.39) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL16670351 0.78 PDK2 (0.41) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190259948-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2019-08-22 US claimed
EP-3101016-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS Idemitsu Kosan Co., Ltd (JP) 2016-12-07 EP claimed
US-20160329492-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2016-11-10 US claimed
US-11616200-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic apparatus IDEMITSU KOSAN CO., LTD. (JP) 2023-03-28 US disclosed
US-20190259948-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2019-08-22 US disclosed
EP-3101016-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS Idemitsu Kosan Co., Ltd (JP) 2016-12-07 EP disclosed
US-20160329492-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2016-11-10 US disclosed
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMATION CO., LTD. (JP) 2011-12-22 US disclosed
EP-2360201-A1 AMINE POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2011-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160329492-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS PIEZO1, RER1, ESR2 MEN1 493/4885KMT2A 1336/4885MAPT 1448/4885
US-11616200-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic apparatus POP1, RER1, EPB41 MEN1 2053/4885KMT2A 1847/4885MAPT 2720/4885
US-20190259948-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS PIEZO1, RER1, ESR2 MEN1 493/4885KMT2A 1336/4885MAPT 1448/4885
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME AHR, HRH3, HRH4 MEN1 942/4885KMT2A 267/4885MAPT 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.