Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.53 |
| ▸ | PDE2A | O00408 | 5/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | PDE6A | P16499 | 1/20 | 0.38 |
| ▸ | PDE6G | P18545 | 1/20 | 0.38 |
| ▸ | PDE6B | P35913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20033422 | 0.95 | PDE10A (0.53) | PDE10APDE2APDE7ACYP1A2METAP2 | |
| SCHEMBL20032698 | 0.84 | MEN1 (0.48) | PDE10APDE2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL20033425 | 0.79 | KIF11 (0.49) | ALDH1A1MAPTKDM4ES1PR1KIF11 | |
| SCHEMBL20032701 | 0.78 | MEN1 (0.48) | PDE10APDE2ACYP1A2GPBAR1MEN1 | |
| SCHEMBL20033417 | 0.74 | KDM4E (0.50) | PDE10APDE2AMETAP2MEN1KMT2A | |
| SCHEMBL29639042 | 0.74 | KDM4E (0.50) | PDE10APDE2AMETAP2MEN1KMT2A | |
| SCHEMBL20033419 | 0.73 | KIF11 (0.49) | ALDH1A1MAPTKDM4ES1PR1KIF11 | |
| SCHEMBL1024552 | 0.73 | PDE10A (0.49) | PDE10APDE2APDE7ACYP1A2METAP2 | |
| SCHEMBL356013 | 0.73 | PDE10A (0.58) | PDE10APDE2APDE7ACYP1A2METAP2 | |
| SCHEMBL20032699 | 0.72 | TLR9 (0.60) | ALDH1A1MAPTKDM4ETOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| EP-3060557-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| WO-2015059088-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015059088-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | CHRM1, CHRM2, ACHE | PDE10A 2739/4885PDE2A 1173/4885PDE7A 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.