Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11853681 | 0.80 | LMNA (0.50) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL3359553 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRCA1LMNAHSD17B10 | |
| SCHEMBL9515830 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL11024154 | 0.71 | — | — | |
| SCHEMBL29193549 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL18279913 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL38661721 | 0.69 | — | — | |
| SCHEMBL28989700 | 0.67 | — | — | |
| SCHEMBL29124770 | 0.67 | — | — | |
| Acetone SCHEMBL4068896 | 0.64 | LMNA (0.43) | ALDH1A1TSHRCA1LMNACA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060568-B1 | METHOD FOR THE SYNTHESIS OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID | MONSANTO TECHNOLOGY LLC (US) | 2019-04-03 | — | — | EP | disclosed |
| CN-105829327-B | Process for the synthesis of ethane-1-hydroxy-1, 1-diphosphonic acid | 孟山都技术有限责任公司 | 2018-11-20 | — | — | CN | disclosed |
| US-9777027-B2 | Method for the synthesis of ethane-1-hydroxy-1,1-diphosphonic acid | STRAITMARK HOLDING AG (CH) | 2017-10-03 | — | — | US | disclosed |
| US-20160264608-A1 | Method For The Synthesis Of Ethane-1-Hydroxy-1,1-Diphosphonic Acid | MONSANTO TECHNOLOGY LLC | 2016-09-15 | — | — | US | disclosed |
| EP-3060568-A1 | METHOD FOR THE SYNTHESIS OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID | Straitmark Holding AG (CH) | 2016-08-31 | — | — | EP | disclosed |
| CN-105829327-A | Process for the synthesis of ethane-1-hydroxy-1, 1-diphosphonic acid | 斯特雷特马克控股股份公司 | 2016-08-03 | — | — | CN | disclosed |
| WO-2015059288-A1 | METHOD FOR THE SYNTHESIS OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID | STRAITMARK HOLDING AG (CH) | 2015-04-30 | — | — | WO | disclosed |