Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667294 | 0.92 | IKBKE (0.60) | TBK1IKBKE | |
| SCHEMBL1667823 | 0.89 | TBK1 (0.65) | TBK1IKBKE | |
| SCHEMBL12274506 | 0.88 | TBK1 (0.66) | TBK1IKBKE | |
| SCHEMBL1669891 | 0.88 | IKBKE (0.57) | TBK1IKBKE | |
| SCHEMBL1667109 | 0.84 | IKBKE (0.68) | TBK1IKBKE | |
| SCHEMBL1667335 | 0.84 | IKBKE (0.45) | TBK1IKBKE | |
| SCHEMBL1667527 | 0.83 | IKBKE (0.80) | TBK1IKBKE | |
| SCHEMBL1667176 | 0.83 | TBK1 (0.65) | TBK1IKBKE | |
| SCHEMBL1669648 | 0.83 | TBK1 (0.65) | TBK1IKBKE | |
| SCHEMBL13279962 | 0.83 | IKBKE (0.66) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | claimed |
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |