Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670819 | 0.82 | PTGES (0.39) | PTGES | |
| SCHEMBL15169717 | 0.80 | PTGES (0.44) | PTGES | |
| SCHEMBL16671439 | 0.79 | PTGES (0.44) | PTGES | |
| SCHEMBL18809972 | 0.78 | PTGES (0.43) | PTGES | |
| SCHEMBL18810062 | 0.77 | PTGES (0.42) | PTGES | |
| Hydrochloric Acid SCHEMBL20489881 | 0.76 | PTGES (0.42) | PTGES | |
| Hydrochloric Acid SCHEMBL29417012 | 0.76 | PTGES (0.42) | PTGES | |
| SCHEMBL15169817 | 0.75 | PTGES (0.45) | PTGES | |
| SCHEMBL18887626 | 0.75 | ERCC1 (0.50) | PTGES | |
| SCHEMBL1563200 | 0.72 | BDKRB2 (0.44) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015059618-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015059618-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-30 | — | — | WO | disclosed |