Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863306 | 1.00 | CYP3A4 (0.50) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL16672004 | 0.94 | ESR1 (0.57) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL15946722 | 0.94 | ESR1 (0.57) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL18774621 | 0.92 | CYP3A4 (0.42) | CYP3A4ESR1ESR2TSHRAR | |
| Bisphenol A SCHEMBL30959812 | 0.88 | CYP3A4 (0.50) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL19562991 | 0.88 | ALDH1A1 (0.62) | CYP3A4ESR1ESR2TSHRAR | |
| Bisphenol A SCHEMBL7195186 | 0.86 | CYP3A4 (0.53) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL19308013 | 0.86 | ESR2 (0.52) | CYP3A4ESR1ESR2TSHRAR | |
| Bisphenol A SCHEMBL16446907 | 0.86 | ESR1 (0.59) | CYP3A4ESR1ESR2TSHRAR | |
| SCHEMBL18774620 | 0.85 | ESR1 (0.47) | CYP3A4ESR1ESR2TSHRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018286-B2 | Flame retardant polycarbonate compositions, methods of manufacture thereof and articles comprising the same | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-04-28 | — | — | US | disclosed |