SCHEMBL16673148

SCHEMBL16673148

Cc1ccc(CCOC(=O)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.64
ESR2 Q92731 1/20 0.64
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
LMNA P02545 3/20 0.59
TDP1 Q9NUW8 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.54
MAPT P10636 2/20 0.54
TP53 P04637 2/20 0.53
HTT P42858 1/20 0.53
CYP3A4 P08684 2/20 0.52
CYP1A2 P05177 1/20 0.52
GAA P10253 1/20 0.52
CYP2C19 P33261 1/20 0.52
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
KMT2A Q03164 1/20 0.51
CHRM2 P08172 2/20 0.51
CHRM4 P08173 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8108520 0.93 ESR1 (0.73) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL13207352 0.91 RAB9A (0.62) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL14722402 0.90 NPC1 (0.72) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL17552330 0.88 ESR1 (0.66) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL16672652 0.88 TDP1 (0.65) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL16672663 0.88 TDP1 (0.65) ESR1ESR2NPC1RAB9ALMNA
Phenethyl Benzoate SCHEMBL4351681 0.88 ESR1 (0.80) ESR1ESR2NPC1RAB9ALMNA
Phenethyl Benzoate SCHEMBL168823 0.88 ESR1 (0.80) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL8804821 0.85 ESR1 (0.67) ESR1ESR2NPC1RAB9ALMNA
SCHEMBL5375263 0.85 ESR1 (0.66) ESR1ESR2NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2869389-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME MITSUBISHI CHEM CORP (JP) 2019-11-13 EP disclosed
US-10320030-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-11 US disclosed
US-9273083-B2 Nickel fluorinating complexes and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-03-01 US disclosed
US-20150252067-A1 NICKEL FLUORINATING COMPLEXES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-09-10 US disclosed
US-20150140448-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
EP-2869389-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME Mitsubishi Chemical Corporation (JP) 2015-05-06 EP disclosed
CN-104412441-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2015-03-11 CN disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B ESR1 3991/4885ESR2 2519/4885NPC1 865/4885
US-20150252067-A1 NICKEL FLUORINATING COMPLEXES AND USES THEREOF SLC39A3, SLC39A14, SLC39A7 ESR1 2303/4885ESR2 3001/4885NPC1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.