Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.54 |
| ▸ | OGFRL1 | Q5TC84 | 9/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120041 | 0.85 | OPRM1 (0.66) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| Citric Acid SCHEMBL2198497 | 0.85 | OPRM1 (0.54) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL1119615 | 0.78 | OPRM1 (0.70) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL3407050 | 0.73 | OPRM1 (0.80) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL3411311 | 0.71 | OPRM1 (0.74) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL15642831 | 0.69 | OPRM1 (0.74) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL3406064 | 0.68 | OPRM1 (1.00) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL3413563 | 0.68 | OPRM1 (0.80) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL1119618 | 0.67 | OPRM1 (0.48) | OPRM1OPRL1OGFRL1OPRD1OPRK1 | |
| SCHEMBL1119831 | 0.67 | OPRM1 (0.86) | OPRM1OPRL1OGFRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280941-B1 | (HETERO-)ARYL CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |