SCHEMBL16675160

SCHEMBL16675160

COC(=O)c1ccc(NC(=O)c2cc(NC(=O)c3ccc(C(=O)OC)cc3)cc(NC(=O)c3cccc(C(=O)OC)c3)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.68
MEN1 O00255 5/20 0.68
RAB9A P51151 4/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
NPC1 O15118 3/20 0.68
TP53 P04637 2/20 0.68
ALDH1A1 P00352 1/20 0.68
PKM P14618 1/20 0.68
HPGD P15428 1/20 0.68
MAPK1 P28482 1/20 0.68
PTPN1 P18031 1/20 0.65
PTPN11 Q06124 1/20 0.65
LMNA P02545 1/20 0.64
PLAU P00749 4/20 0.62
KDM4E B2RXH2 1/20 0.61
ATM Q13315 1/20 0.60
GPR17 Q13304 1/20 0.60
MAPT P10636 1/20 0.57
PLAT P00750 2/20 0.56
PLG P00747 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16677984 0.97 MEN1 (0.72) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL16681258 0.91 RAB9A (0.75) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL6243177 0.86 NPC1 (0.72) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL25138816 0.85 RAB9A (0.91) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL6242208 0.85 RAB9A (0.84) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL6014174 0.84 RAB9A (0.71) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL62930 0.83 PTPN1 (0.90) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL11710023 0.83 RAB9A (0.76) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL8660366 0.83 NPC1 (0.83) KMT2AMEN1RAB9ASMN1; SMN2NPC1
SCHEMBL6263820 0.83 NPC1 (0.83) KMT2AMEN1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed