SCHEMBL16675164

SCHEMBL16675164

O=C(Nc1cc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.79
NR1H4 Q96RI1 2/20 0.69
HDAC1 Q13547 1/20 0.63
CASP3 P42574 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
KCNQ3 O43525 1/20 0.60
KCNQ2 O43526 1/20 0.60
KCNE1 P15382 1/20 0.60
KCNQ1 P51787 1/20 0.60
RAB9A P51151 3/20 0.59
NPC1 O15118 2/20 0.59
TP53 P04637 1/20 0.59
RECQL P46063 1/20 0.59
EPHX1 P07099 1/20 0.58
PNLIP P16233 1/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ASF1A Q9Y294 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16677954 0.97 PGR (0.79) PGRNR1H4HDAC1CASP3SENP8
SCHEMBL22192258 0.92 PGR (0.93) PGRNR1H4HDAC1CASP3SENP8
SCHEMBL16677982 0.90 PGR (0.83) PGRNR1H4HDAC1CASP3SENP8
SCHEMBL5694520 0.89 PGR (1.00) PGRNR1H4HDAC1KCNQ3KCNQ2
SCHEMBL19619022 0.89 PGR (0.86) PGRNR1H4HDAC1CASP3SENP8
SCHEMBL16681530 0.88 PGR (0.60) PGRNR1H4RAB9ANPC1TP53
SCHEMBL8361085 0.87 PGR (0.96) PGRNR1H4HDAC1RAB9ANPC1
SCHEMBL7259582 0.86 PGR (0.81) PGRNR1H4HDAC1KCNQ3KCNQ2
SCHEMBL19501833 0.86 PGR (0.81) PGRNR1H4HDAC1KCNQ3KCNQ2
SCHEMBL19491383 0.85 NR1H4 (0.74) PGRNR1H4RAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed