SCHEMBL22192258

SCHEMBL22192258

O=C(Nc1ccc(Oc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.93
HDAC1 Q13547 1/20 0.71
NR1H4 Q96RI1 2/20 0.69
KCNQ3 O43525 1/20 0.68
KCNQ2 O43526 1/20 0.68
KCNE1 P15382 1/20 0.68
KCNQ1 P51787 1/20 0.68
RAB9A P51151 4/20 0.68
NPC1 O15118 3/20 0.68
TP53 P04637 1/20 0.68
RECQL P46063 1/20 0.68
EPHX1 P07099 1/20 0.67
PNLIP P16233 1/20 0.66
CASP3 P42574 1/20 0.65
SENP8 Q96LD8 1/20 0.65
SENP7 Q9BQF6 1/20 0.65
SENP6 Q9GZR1 1/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
KDM4E B2RXH2 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694520 0.96 PGR (1.00) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL19619022 0.96 PGR (0.86) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL8361085 0.94 PGR (0.96) PGRHDAC1NR1H4RAB9ANPC1
SCHEMBL19501833 0.93 PGR (0.81) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL7259582 0.93 PGR (0.81) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL6140934 0.92 PGR (0.79) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL16677954 0.92 PGR (0.79) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL14363134 0.92 PGR (0.79) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL16675164 0.92 PGR (0.79) PGRHDAC1NR1H4KCNQ3KCNQ2
SCHEMBL94749 0.92 PGR (0.79) PGRHDAC1NR1H4KCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703911-B2 Organic colorant, coloring composition, and inkjet ink RICOH COMPANY, LTD. (JP) 2020-07-07 US disclosed