Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386738 | 0.75 | RAB9A (0.68) | RAB9AMAOBSMPD1ADAM17PTPN1 | |
| SCHEMBL13277597 | 0.73 | MAOB (0.48) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL13277598 | 0.73 | MAOB (0.48) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL7339603 | 0.73 | MAOB (0.53) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL7339607 | 0.73 | MAOB (0.53) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL1670147 | 0.73 | KCNH2 (0.46) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL1670144 | 0.73 | KCNH2 (0.46) | RAB9AKCNH2GPR119MAOBSMPD1 | |
| SCHEMBL29741480 | 0.71 | MAOB (0.81) | RAB9AMAOBSMPD1MAOAHRH3 | |
| SCHEMBL18664184 | 0.71 | MAOB (0.81) | RAB9AMAOBSMPD1MAOAHRH3 | |
| SCHEMBL20848350 | 0.71 | MAOB (0.60) | RAB9AKCNH2MAOBSMPD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042217-A1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | ORYZON GENOMICS S.A. (ES) | 2011-04-14 | — | — | WO | disclosed |