Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339603 | 1.00 | MAOB (0.53) | MAOBRAB9ALTA4HPTPN1GPR119 | |
| SCHEMBL25317908 | 0.91 | DPP4 (0.45) | MAOBLTA4HDPP4FAPDPP8 | |
| SCHEMBL7338836 | 0.86 | LTA4H (0.65) | MAOBLTA4HLAP3PPARA | |
| SCHEMBL7339057 | 0.86 | LTA4H (0.65) | MAOBLTA4HLAP3PPARA | |
| SCHEMBL7341088 | 0.86 | MAOB (0.55) | MAOBRAB9ALTA4HLAP3ALDH1A1 | |
| SCHEMBL7341100 | 0.86 | MAOB (0.55) | MAOBRAB9ALTA4HLAP3ALDH1A1 | |
| SCHEMBL7338844 | 0.86 | LTA4H (0.65) | MAOBLTA4HLAP3PPARA | |
| Hydrochloric Acid SCHEMBL3499901 | 0.85 | LTA4H (0.55) | MAOBRAB9ALTA4HLAP3KCNH2 | |
| Hydrochloric Acid SCHEMBL3499899 | 0.85 | LTA4H (0.55) | MAOBRAB9ALTA4HLAP3KCNH2 | |
| SCHEMBL7342884 | 0.84 | MAOB (0.52) | MAOBRAB9ALTA4HGPR119LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |