SCHEMBL16675185

SCHEMBL16675185

COc1ccccc1C(=O)Nc1cc(NC(=O)c2ccccc2OC)nc(NC(=O)c2ccccc2OC)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.71
RAB9A P51151 5/20 0.63
NPC1 O15118 5/20 0.63
GAA P10253 2/20 0.63
KMT2A Q03164 2/20 0.63
MEN1 O00255 1/20 0.63
TP53 P04637 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
KCNK3 O14649 3/20 0.60
KCNK9 Q9NPC2 3/20 0.60
MAPT P10636 4/20 0.57
ADORA3 P0DMS8 1/20 0.57
ADORA2A P29274 1/20 0.57
ADORA1 P30542 1/20 0.57
PKM P14618 1/20 0.56
PAX8 Q06710 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MAPK1 P28482 2/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822334 0.84 RXFP1 (0.64) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL28861390 0.79 RXFP1 (0.61) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL15305682 0.78 NPC1 (0.48) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL28229112 0.78 RXFP1 (0.57) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL822361 0.78 RAB9A (0.52) RXFP1RAB9ANPC1KMT2AMEN1
SCHEMBL29764989 0.78 RAB9A (1.00) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL14637696 0.78 RAB9A (1.00) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL3418714 0.77 RXFP1 (0.67) RXFP1RAB9ANPC1GAAKMT2A
Hydrochloric Acid SCHEMBL29765136 0.77 RAB9A (0.97) RXFP1RAB9ANPC1GAAKMT2A
SCHEMBL11609173 0.75 ADORA3 (0.60) RXFP1RAB9ANPC1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed