SCHEMBL16675193

SCHEMBL16675193

CCN(CC)c1cccc(C(=O)Nc2cc(NC(=O)c3cccc(N(C)C)c3)nc(NC(=O)c3cccc(N(CC)CC)c3)n2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 3/20 0.51
HPGD P15428 2/20 0.51
ALOX15 P16050 1/20 0.51
RAB9A P51151 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 2/20 0.48
PDE5A O76074 1/20 0.47
SMN1; SMN2 Q16637 5/20 0.46
GFER P55789 3/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
TP53 P04637 1/20 0.46
LMNA P02545 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16677983 0.77 MAPT (0.53) MAPTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL16677945 0.77 KCNK3 (0.55) MAPTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL821784 0.76 GRM5 (0.54) MAPTKDM4ERAB9AMEN1KMT2A
SCHEMBL822347 0.75 L3MBTL1 (0.56) MAPTRAB9AMEN1KMT2ANPC1
SCHEMBL16677949 0.75 KCNK3 (0.55) MAPTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL9646566 0.74 MAPT (0.62) MAPTALDH1A1RAB9AMEN1KMT2A
SCHEMBL15305709 0.74 GRM5 (0.68) RAB9AMEN1KMT2ANPC1SMN1; SMN2
SCHEMBL821395 0.72 GRM5 (0.58) RAB9AMEN1KMT2ANPC1TP53
SCHEMBL13702275 0.70 KDM4E (0.62) MAPTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL821945 0.70 L3MBTL1 (0.59) MAPTRAB9AMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed