Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | RORC | P51449 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GLI1 | P08151 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.58 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.58 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675291 | 1.00 | GPBAR1 (0.64) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL16675292 | 0.90 | RORC (0.55) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL16675280 | 0.90 | RORC (0.55) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL16677969 | 0.89 | GPBAR1 (0.79) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL15362683 | 0.89 | GPBAR1 (0.79) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL17281331 | 0.86 | GPBAR1 (0.83) | GPBAR1PRKCD | |
| SCHEMBL17124290 | 0.86 | GPBAR1 (0.81) | GPBAR1PRKCDPTPN1RORCUSP2 | |
| SCHEMBL15362614 | 0.85 | GPBAR1 (0.68) | GPBAR1PRKCDNT5E | |
| SCHEMBL15854472 | 0.85 | GPBAR1 (0.68) | GPBAR1PRKCDNT5E | |
| SCHEMBL18799005 | 0.85 | GPBAR1 (0.68) | GPBAR1PRKCDNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150119373-A1 | NOVEL BETULINIC ACID DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119373-A1 | NOVEL BETULINIC ACID DERIVATIVES AS HIV INHIBITORS | BET1, PGGT1B, RABGGTB | GPBAR1 311/4885PRKCD 2367/4885PTPN1 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.