Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646865 | 0.84 | LMNA (0.64) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16675429 | 0.80 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16560502 | 0.79 | LMNA (0.66) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17145379 | 0.78 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14646864 | 0.78 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8896837 | 0.78 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17120815 | 0.78 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL25664896 | 0.75 | LMNA (0.60) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17145899 | 0.75 | LMNA (0.60) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2683971 | 0.75 | LMNA (0.60) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403826-B2 | Compositions and methods for the treatment of inflammatory disorders | CELLIX BIO PRIVATE LIMITED (IN) | 2016-08-02 | — | — | US | disclosed |
| US-20150119409-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | CELLIX BIO PRIVATE LIMITED (IN) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119409-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | BRCA1, PTGER1, EPAS1 | LMNA 842/4885KDM4E 4392/4885ALDH1A1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.