Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646865 | 0.81 | LMNA (0.64) | LMNAAOC3KDM4EALDH1A1HPGD | |
| SCHEMBL25609280 | 0.81 | AOC3 (0.57) | LMNAAOC3CYP2C19L3MBTL1MAPT | |
| SCHEMBL16675429 | 0.78 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16675424 | 0.78 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4052938 | 0.77 | ESR1 (0.59) | LMNAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16560502 | 0.77 | LMNA (0.66) | LMNAAOC3KDM4EALDH1A1HPGD | |
| SCHEMBL17119506 | 0.76 | AOC3 (0.48) | LMNAAOC3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17120817 | 0.76 | AOC3 (0.45) | LMNAAOC3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17120815 | 0.76 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14646864 | 0.76 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9221473-A | — | — | None | — | — | JP | disclosed |
| JP-H09221473-A | 3-HYDROXY-4-AMINOMETHYLPYRIDINE DERIVATIVE AND MAILLARD REACTION INHIBITOR CONTAINING THE SAME | KISSEI PHARMACEUT CO LTD | 1997-08-26 | — | — | JP | disclosed |