Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19890324 | 0.96 | THRB (0.64) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL17743609 | 0.90 | THRB (0.77) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL24595537 | 0.90 | THRB (0.66) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL12973262 | 0.89 | THRB (0.70) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL14900267 | 0.89 | THRB (0.74) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL22960119 | 0.87 | THRB (0.66) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL13642702 | 0.87 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL15697263 | 0.87 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL13433215 | 0.86 | ALDH1A1 (0.58) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL126691 | 0.86 | THRB (0.81) | THRBTSHRALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150117896-A1 | CLEANING BLADE AND IMAGE FORMING APPARATUS INCLUDING SAME | RICOH COMPANY, LTD. (JP) | 2015-04-30 | — | — | US | disclosed |