Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027660 | 1.00 | POLB (0.55) | POLBKMT2AMEN1MAOANPC1 | |
| SCHEMBL12027654 | 1.00 | POLB (0.55) | POLBKMT2AMEN1MAOANPC1 | |
| Hydrochloric Acid SCHEMBL4711056 | 0.90 | POLB (0.60) | POLBKMT2AMEN1MAOANPC1 | |
| Hydrochloric Acid SCHEMBL4711057 | 0.90 | POLB (0.60) | POLBKMT2AMEN1MAOANPC1 | |
| SCHEMBL5790489 | 0.86 | POLB (0.69) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13841211 | 0.84 | POLB (0.56) | POLBKMT2AMEN1MAOANPC1 | |
| SCHEMBL13450089 | 0.81 | POLB (0.63) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3154235 | 0.81 | POLB (0.63) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL24636855 | 0.80 | POLB (0.66) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19750331 | 0.79 | MEN1 (0.64) | POLBKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |