Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667583 | 1.00 | BRD4 (0.33) | BRD4KMT2ANPSR1ESR1ESR2 | |
| SCHEMBL1667700 | 0.83 | BRD4 (0.36) | BRD4KMT2AESR1ESR2 | |
| SCHEMBL1667699 | 0.83 | BRD4 (0.36) | BRD4KMT2AESR1ESR2 | |
| SCHEMBL1667589 | 0.83 | BRD4 (0.33) | BRD4KMT2ANPSR1ESR1ESR2 | |
| SCHEMBL1670809 | 0.82 | BRD4 (0.34) | BRD4ESR1ESR2 | |
| SCHEMBL1670805 | 0.82 | BRD4 (0.34) | BRD4ESR1ESR2 | |
| SCHEMBL1667629 | 0.82 | BRD4 (0.34) | BRD4KMT2ANPSR1ESR1ESR2 | |
| SCHEMBL1667631 | 0.82 | BRD4 (0.34) | BRD4KMT2ANPSR1ESR1ESR2 | |
| SCHEMBL1077417 | 0.80 | ESR1 (0.38) | BRD4KMT2ANPSR1ESR1ESR2 | |
| SCHEMBL1077420 | 0.80 | ESR1 (0.38) | BRD4KMT2ANPSR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |