Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670809 | 1.00 | BRD4 (0.34) | BRD4CREBBPARESR1ESR2 | |
| SCHEMBL1672972 | 0.87 | TSHR (0.41) | BRD4CREBBPARBRD2TSHR | |
| SCHEMBL1667583 | 0.82 | BRD4 (0.33) | BRD4ESR1ESR2 | |
| SCHEMBL1667584 | 0.82 | BRD4 (0.33) | BRD4ESR1ESR2 | |
| SCHEMBL12800297 | 0.82 | BRD4 (0.38) | BRD4CREBBPARESR1ESR2 | |
| SCHEMBL1671029 | 0.81 | — | — | |
| SCHEMBL1671031 | 0.81 | — | — | |
| SCHEMBL2312965 | 0.81 | ERN1 (0.34) | BRD4 | |
| SCHEMBL2307797 | 0.81 | ERN1 (0.34) | BRD4 | |
| SCHEMBL1077417 | 0.81 | ESR1 (0.38) | BRD4CREBBPESR1ESR2BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |