Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | MC4R | P32245 | 1/20 | 0.78 |
| ▸ | SCN4A | P35499 | 1/20 | 0.78 |
| ▸ | MC3R | P41968 | 1/20 | 0.78 |
| ▸ | HTR3A | P46098 | 1/20 | 0.78 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264270 | 0.97 | MAPT (0.74) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21261956 | 0.96 | MAPT (0.72) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL24083458 | 0.94 | MAPT (0.74) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21264265 | 0.93 | MAPT (0.72) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21261951 | 0.93 | MAPT (0.80) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21264312 | 0.92 | MAPT (0.66) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21264151 | 0.92 | LMNA (0.74) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21264244 | 0.91 | LMNA (0.68) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL16709550 | 0.91 | LMNA (0.82) | MAPTLMNASCN3AALDH1A1CYP3A4 | |
| SCHEMBL21261870 | 0.91 | LMNA (0.72) | MAPTLMNASCN3AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750870-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2020-12-16 | — | — | EP | disclosed |
| US-9492409-B2 | Compositions and methods for the treatment of local pain | CELLIX BIO PRIVATE LIMITED (IN) | 2016-11-15 | — | — | US | disclosed |
| US-20150119423-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LOCAL PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119423-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LOCAL PAIN | TRPV1, SCN3A, OPRK1 | MAPT 933/4885LMNA 3273/4885SCN3A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.