Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.56 |
| ▸ | BRAF | P15056 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13955883 | 0.89 | IGF1R (0.59) | IGF1RBRAFEGFRKDRCDK2 | |
| SCHEMBL1116462 | 0.82 | IGF1R (0.79) | IGF1RMEN1KMT2AEGFRKDR | |
| SCHEMBL17394819 | 0.82 | POLB (0.56) | IGF1RMEN1KMT2AKDREPHB4 | |
| SCHEMBL13325996 | 0.81 | PTK2 (0.62) | IGF1RMEN1KMT2AEGFRKDR | |
| SCHEMBL16675210 | 0.79 | POLB (0.64) | BRAFMEN1KMT2A | |
| SCHEMBL12857672 | 0.79 | BRAF (0.82) | BRAF | |
| SCHEMBL1116426 | 0.77 | IGF1R (0.74) | IGF1RMEN1KMT2AEGFRKDR | |
| SCHEMBL8348483 | 0.77 | DYRK1A (0.48) | IGF1RBRAFEGFRKDRINSR | |
| SCHEMBL6976835 | 0.77 | IGF1R (0.78) | IGF1RMEN1KMT2AEGFRKDR | |
| SCHEMBL6981464 | 0.77 | IGF1R (0.78) | IGF1RBRAFMEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150114257-A1 | METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY | Konica Minolta, Inc. (JP) | 2015-04-30 | — | — | US | disclosed |