Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16678810 | 0.84 | GPBAR1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL14881862 | 0.83 | GPBAR1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL16678460 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL30919489 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL14881994 | 0.76 | GPBAR1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL16678442 | 0.76 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL14881812 | 0.76 | GPBAR1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL14881800 | 0.76 | GPBAR1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL14881510 | 0.76 | GPBAR1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL31415205 | 0.75 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126530-A1 | Novel Substituted Imidazopyrimidines as Gpbar1 Receptor Modulators | TORRENT PHARMACEUTICALS LIMITED (IN) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126530-A1 | Novel Substituted Imidazopyrimidines as Gpbar1 Receptor Modulators | GPBAR1, GPER1, GPR55 | ALDH1A1 378/4885KDM4E 4550/4885HPGD 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.