Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667893 | 0.84 | MEN1 (0.44) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1665674 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2065858 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10178021 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL703717 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30777879 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3206868 | 0.74 | MAPT (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20970479 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3578655 | 0.71 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18209126 | 0.70 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |