Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667937 | 1.00 | CPB2 (0.44) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL20834533 | 0.87 | CPB2 (0.39) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14199860 | 0.86 | CPB2 (0.41) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7738755 | 0.86 | CPB2 (0.49) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7738753 | 0.86 | CPB2 (0.49) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3685448 | 0.84 | CPB2 (0.50) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3685446 | 0.84 | CPB2 (0.50) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3839540 | 0.83 | CPB2 (0.55) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3845157 | 0.83 | CPB2 (0.55) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11867249 | 0.83 | CPB2 (0.39) | CPB2CPB1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490709-B1 | PEPTIDIC GLP-2 AGONISTS | FERRING BV (NL) | 2014-11-26 | — | — | EP | disclosed |
| US-8580918-B2 | Peptidic GLP-2 agonists | FERRING B.V. (NL) | 2013-11-12 | — | — | US | disclosed |
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | FERRING B.V. (NL) | 2012-09-13 | — | — | US | disclosed |
| EP-2314616-A1 | Peptidic GLP-2 agonists | Ferring B.V. (NL) | 2011-04-27 | — | — | EP | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | CPB2 16/4885CPB1 67/4885ALDH1A1 1305/4885 |
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | GLP1R, GIPR, IAPP | CPB2 596/4885CPB1 1160/4885ALDH1A1 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.