Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875965 | 0.81 | MAPT (0.48) | ALDH1A1KDM4EKMT2ACYP2C9TRPV4 | |
| SCHEMBL13342828 | 0.79 | TSHR (0.47) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL936003 | 0.79 | EPAS1 (0.43) | EPAS1ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL9145564 | 0.78 | MAPT (0.49) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL16680208 | 0.78 | KDM4E (0.35) | EPAS1ALDH1A1KDM4EKMT2ACYP1A2 | |
| SCHEMBL29198847 | 0.78 | TRPV4 (0.56) | EPAS1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL936370 | 0.78 | KDM4E (0.35) | EPAS1ALDH1A1KDM4EKMT2ACYP1A2 | |
| SCHEMBL16680513 | 0.78 | PPARG (0.46) | EPAS1ALDH1A1TRPV4PPARAS1PR4 | |
| SCHEMBL11568855 | 0.78 | PKM (0.47) | EPAS1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL8608378 | 0.77 | TSHR (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683244-B2 | Method for controlling plant parasitic nematodes | YAMASHITA THOMAS T (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190023627-A1 | Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same | YAMASHITA THOMAS T (US) | 2019-01-24 | — | — | US | disclosed |
| US-10106472-B2 | Compositions for controlling plant parasitic nematodes and methods for using same | YAMASHITA THOMAS T (US) | 2018-10-23 | — | — | US | disclosed |
| US-20170226024-A1 | Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same | YAMASHITA THOMAS T (US) | 2017-08-10 | — | — | US | disclosed |
| US-9661857-B2 | Compositions for controlling plant parasitic nematodes | YAMASHITA THOMAS T (US) | 2017-05-30 | — | — | US | disclosed |
| EP-2984060-A1 | COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME | Yamashita, Thomas T. (US) | 2016-02-17 | — | — | EP | disclosed |
| US-20150125435-A1 | Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same | YAMASHITA THOMAS T (US) | 2015-05-07 | — | — | US | disclosed |
| WO-2015065581-A1 | COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME | YAMASHITA THOMAS T (US) | 2015-05-07 | — | — | WO | disclosed |