Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668114 | 1.00 | BRD4 (0.34) | BRD4NSD3NTRK1PIM1CHEK1 | |
| SCHEMBL1075876 | 0.86 | CYP1A2 (0.34) | BRD4NSD3MEN1USP2ALDH1A1 | |
| SCHEMBL1075873 | 0.86 | CYP1A2 (0.34) | BRD4NSD3MEN1USP2ALDH1A1 | |
| SCHEMBL1668122 | 0.84 | BRD4 (0.34) | BRD4NSD3MEN1USP2ALDH1A1 | |
| SCHEMBL1670150 | 0.83 | BRD4 (0.35) | BRD4NTRK1PIM1CHEK1CDK2 | |
| SCHEMBL1670148 | 0.83 | BRD4 (0.35) | BRD4NTRK1PIM1CHEK1CDK2 | |
| SCHEMBL1667699 | 0.82 | BRD4 (0.36) | BRD4NTRK1PIM1CHEK1CDK2 | |
| SCHEMBL1667700 | 0.82 | BRD4 (0.36) | BRD4NTRK1PIM1CHEK1CDK2 | |
| SCHEMBL1076829 | 0.75 | PTGDR2 (0.36) | BRD4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL1075922 | 0.75 | CYP1A2 (0.34) | BRD4MEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |