Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670150 | 1.00 | BRD4 (0.35) | BRD4FTOGRM4PDE2APDE10A | |
| SCHEMBL1667700 | 0.85 | BRD4 (0.36) | BRD4ADORA3CHEK1NTRK1PIM1 | |
| SCHEMBL1667699 | 0.85 | BRD4 (0.36) | BRD4ADORA3CHEK1NTRK1PIM1 | |
| SCHEMBL1670152 | 0.84 | FTO (0.35) | BRD4FTOGRM4PDE2APDE10A | |
| SCHEMBL1668119 | 0.83 | BRD4 (0.34) | BRD4CHEK1NTRK1PIM1CDK2 | |
| SCHEMBL1668114 | 0.83 | BRD4 (0.34) | BRD4CHEK1NTRK1PIM1CDK2 | |
| SCHEMBL1077881 | 0.76 | ALOX15 (0.37) | BRD4FTOCYP3A4CYP2C9BRD2 | |
| SCHEMBL1077878 | 0.76 | ALOX15 (0.37) | BRD4FTOCYP3A4CYP2C9BRD2 | |
| SCHEMBL1670091 | 0.74 | ESR1 (0.34) | BRD4ADORA3CHEK1NTRK1PIM1 | |
| SCHEMBL1670089 | 0.74 | ESR1 (0.34) | BRD4ADORA3CHEK1NTRK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |