SCHEMBL1668264

SCHEMBL1668264

C=C(C(=O)O)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EIF2AK2 P19525 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
TDP1 Q9NUW8 1/20 0.32
AKR1C4 P17516 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
AKR1C1 Q04828 1/20 0.31
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3226979 0.79 CYP1A2 (0.31)
SCHEMBL49516 0.78 EIF2AK2 (0.45) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL27476740 0.77 MAPT (0.36) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
Methacrylic Acid SCHEMBL28528157 0.74 EIF2AK2 (0.42) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL29478355 0.73 EIF2AK2 (0.41) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL4656443 0.71 EIF2AK2 (0.39) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL11813056 0.71 EIF2AK2 (0.39) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL9629952 0.71 EIF2AK2 (0.41) EIF2AK2CSNK2A2CSNK2BCSNK2A1
SCHEMBL9629950 0.71 EIF2AK2 (0.41) EIF2AK2CSNK2A2CSNK2BCSNK2A1
SCHEMBL38662144 0.70 EIF2AK2 (0.38) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488590-A1 HIGHLY REFRACTIVE, SCRATCHPROOF TIO2 COATINGS IN MONO- AND MULTILAYERS Bayer MaterialScience AG (DE) 2012-08-22 EP disclosed
WO-2011045275-A1 HIGHLY REFRACTIVE, SCRATCHPROOF TIO2 COATINGS IN MONO- AND MULTILAYERS BAYER MATERIALSCIENCE AG (DE) 2011-04-21 WO disclosed
EP-2154128-B1 Phenylisocyanate based urethane acrylates with high refraction index BAYER MATERIALSCIENCE AG (DE) 2010-12-29 EP disclosed
EP-2154129-A1 Phenylisocyanate based urethanacrylate with high refraction index Bayer MaterialScience AG (DE) 2010-02-17 EP disclosed
EP-2154128-A1 Phenylisocyanate based urethanacrylates with high refraction index Bayer MaterialScience AG (DE) 2010-02-17 EP disclosed
EP-2079811-A1 COATED PRODUCT CONTAINING A HIGHLY REFRACTIVE AND SCRATCH-RESISTANT LAYER Bayer MaterialScience AG (DE) 2009-07-22 EP disclosed
WO-2008040439-A2 COATED PRODUCT CONTAINING A HIGHLY REFRACTIVE AND SCRATCH-RESISTANT LAYER BAYER MATERIALSCIENCE AG (DE) 2008-04-10 WO disclosed
EP-0269821-B1 OPTICAL WAVEGUIDE HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-01 EP disclosed
EP-0269821-A1 Optical waveguide HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-08 EP disclosed
EP-0267459-A1 Transparent polymers HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-18 EP disclosed