SCHEMBL49516

SCHEMBL49516

O=C(O)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EIF2AK2 P19525 1/20 0.45
CSNK2A2 P19784 1/20 0.45
CSNK2B P67870 1/20 0.45
CSNK2A1 P68400 1/20 0.45
AKR1C4 P17516 2/20 0.45
AKR1C3 P42330 2/20 0.45
AKR1C2 P52895 2/20 0.45
AKR1C1 Q04828 2/20 0.45
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
TSHR P16473 3/20 0.41
PTPN1 P18031 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11679713 0.87 TSHR (0.46) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL8941154 0.81 AKR1C4 (0.42) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL605556 0.81 AKR1C3 (0.57) AKR1C4AKR1C3AKR1C2AKR1C1PTPN1
SCHEMBL30555489 0.81 AKR1C3 (0.57) AKR1C4AKR1C3AKR1C2AKR1C1PTPN1
SCHEMBL10868192 0.81 AKR1C4 (0.42) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL7875778 0.81 AKR1C3 (0.52) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL195519 0.81 AKR1C3 (0.42) EIF2AK2CSNK2A2CSNK2BCSNK2A1AKR1C4
SCHEMBL29478355 0.80 EIF2AK2 (0.41) EIF2AK2CSNK2A2CSNK2BCSNK2A1AKR1C4
SCHEMBL28439923 0.79 KDM4E (0.44) EIF2AK2CSNK2A2CSNK2BCSNK2A1AKR1C4
SCHEMBL28171623 0.79 AKR1C4 (0.41) EIF2AK2CSNK2A2CSNK2BCSNK2A1AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117727955-A High-activity halogen element doped non-noble metal oxygen reduction catalyst and preparation method thereof 海南大学 2024-03-19 CN claimed
CN-111499513-B Synthesis method of 2,3,4, 5-tetrabromobenzoate 上海毕得医药科技股份有限公司 2023-03-14 CN claimed
US-20220380608-A1 Flame Retardant Mechanical Foam STAHL INTERNATIONAL B.V. (NL) 2022-12-01 US claimed
EP-4081601-A1 FLAME RETARDANT MECHANICAL FOAM Stahl International B.V. (NL) 2022-11-02 EP claimed
CN-114846090-A Flame-retardant mechanical foam 斯塔尔国际有限公司 2022-08-02 CN claimed
CN-111499513-A Synthetic method of 2,3,4, 5-tetrabromobenzoate 上海毕得医药科技有限公司 2020-08-07 CN claimed
CN-109957222-A A kind of low precipitation flame retardant PBT composition 杭州本松新材料技术股份有限公司 2019-07-02 CN claimed
CN-109836817-A Halogen flame and its application 杭州本松新材料技术股份有限公司 2019-06-04 CN claimed
CN-103570972-B Oligomer mixture, production and as fire retardant application and include its flame retardant polyurethane 朗盛德国有限责任公司 2019-02-01 CN claimed
US-9920081-B2 Halogen-free poly(alkylene phosphates) LANXESS DEUTSCHLAND GMBH (DE) 2018-03-20 US claimed
WO-2005105911-A1 LOW SCORCHING FLAME RETARDANTS FOR POLYURETHANE FOAMS SUPRESTA LLC (US) 2005-11-10 WO claimed
WO-2005016863-A1 PROCESS FOR PRODUCING TETRABROMOBENZOATE ESTERS GREAT LAKES CHEMICAL CORPORATION (US) 2005-02-24 WO claimed
US-20050027139-A1 Process for producing tetrabromobenzoate esters GLCC LAUREL, LLC 2005-02-03 US claimed
EP-0832153-A4 BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS GREAT LAKES CHEMICAL CORP (US) 1998-08-26 EP claimed
EP-0825974-A4 ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS GREAT LAKES CHEMICAL CORP (US) 1998-07-08 EP claimed
EP-0832153-A1 BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS GREAT LAKES CHEMICAL CORPORATION (US) 1998-04-01 EP claimed
EP-0825974-A1 ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS GREAT LAKES CHEMICAL CORPORATION (US) 1998-03-04 EP claimed
US-5637757-A REACTING TETRABROMOPHTHALIC ANHYDRIDE WITH AN ALCOHOL IN PRESENCE OF A DECARBOXYLATION CATALYST GREAT LAKES CHEMICAL CORPORATION (US) 1997-06-10 US claimed
WO-1996032368-A1 ONE-POT SYNTHESIS OF RING-BROMINATED BENZOATE COMPOUNDS GREAT LAKES CHEMICAL CORPORATION (US) 1996-10-17 WO claimed
WO-1996032438-A1 BENZOATES AS FLAME RETARDANTS AND/OR PLASTICIZERS GREAT LAKES CHEMICAL CORPORATION (US) 1996-10-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050027139-A1 Process for producing tetrabromobenzoate esters TECR, ADH1C, ADH1A EIF2AK2 4571/4885CSNK2A2 2075/4885CSNK2B 1369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.