Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49516 | 0.80 | EIF2AK2 (0.45) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL4656443 | 0.78 | EIF2AK2 (0.39) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL11813056 | 0.78 | EIF2AK2 (0.39) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL38662144 | 0.76 | EIF2AK2 (0.38) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL28387358 | 0.76 | TDP1 (0.39) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL1668264 | 0.73 | EIF2AK2 (0.40) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL10434528 | 0.72 | EIF2AK2 (0.43) | EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL9196525 | 0.72 | PTPN1 (0.32) | EIF2AK2CSNK2A2CSNK2BCSNK2A1PTPN1 | |
| SCHEMBL8495472 | 0.70 | MAPT (0.51) | TDP1AKR1C3 | |
| SCHEMBL9629952 | 0.69 | EIF2AK2 (0.41) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390711-B2 | Preparations having improved efficacy as flame retardants | LANXESS DEUTSCHLAND GMBH (DE) | 2022-07-19 | — | — | US | disclosed |
| CN-111234509-B | Formulations, polyurethanes comprising them, processes for their production and their use | 朗盛德国有限责任公司 | 2022-03-01 | — | — | CN | disclosed |