SCHEMBL16684149

SCHEMBL16684149

N#Cc1ccc(OP=O)cc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.57
PGR P06401 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4171092 0.80 AR (0.74) AR
SCHEMBL20221049 0.78 AR (0.62) ARPGR
SCHEMBL13012268 0.78 AR (0.77) ARPGR
SCHEMBL31099416 0.77 AR (0.57) ARPGR
SCHEMBL20720017 0.76 AR (0.56) ARPGR
SCHEMBL2473229 0.76 AR (0.56) ARPGR
SCHEMBL8544583 0.75 AR (0.81) ARPGR
SCHEMBL4196449 0.75 AR (0.59) ARPGR
SCHEMBL6764243 0.75 AR (0.63) ARPGR
SCHEMBL2966262 0.75 AR (0.55) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049200-B1 NOVEL INHIBITORS OF BETA-LACTAMASE METHYLGENE INC (CA) 2015-04-29 EP disclosed