Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823494 | 0.85 | AR (0.55) | ARPGR | |
| SCHEMBL28402380 | 0.84 | MEN1 (0.42) | AR | |
| SCHEMBL28381646 | 0.81 | KIF11 (0.43) | ARPGR | |
| SCHEMBL28209681 | 0.80 | MEN1 (0.47) | — | |
| SCHEMBL20221049 | 0.79 | AR (0.62) | ARPGR | |
| SCHEMBL13715641 | 0.78 | AR (0.61) | ARPGR | |
| SCHEMBL28493696 | 0.78 | AR (0.69) | AR | |
| SCHEMBL28493695 | 0.78 | AR (0.69) | AR | |
| SCHEMBL3710923 | 0.78 | KIF11 (0.51) | AR | |
| SCHEMBL28241743 | 0.77 | AR (0.52) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873917-B | Non-steroidal antiandrogens and selective androgen receptor modulators containing a pyridyl moiety | 恩多研究公司 | 2021-08-10 | — | — | CN | disclosed |
| US-9682960-B2 | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety | ENDORECHERCHE, INC. (CA) | 2017-06-20 | — | — | US | disclosed |
| EP-3083590-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | Endorecherche, Inc. (CA) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015089634-A9 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015089634-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | WO | disclosed |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | US | disclosed |
| WO-2014111871-A1 | 4,5-DIHYDROISOXAZOLE DERIVATIVES AS NAMPT INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-24 | — | — | WO | disclosed |
| US-7776859-B2 | Hexahydroimidazopyrazin-3-one compounds useful as modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-17 | — | — | US | disclosed |
| US-20070088039-A1 | Hexahydroimidazopyrazin-3-one compounds useful as modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088039-A1 | Hexahydroimidazopyrazin-3-one compounds useful as modulators of androgen receptor function | AR, FSHR, NR5A1 | AR 1/4885PGR 75/4885 |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | AR, SHBG, SRD5A1 | AR 1/4885PGR 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.