⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133132 | 0.78 | — | — | |
| SCHEMBL283763 | 0.78 | — | — | |
| SCHEMBL18200138 | 0.78 | — | — | |
| SCHEMBL30586918 | 0.76 | METAP2 (0.32) | — | |
| SCHEMBL15616805 | 0.75 | — | — | |
| SCHEMBL25498928 | 0.74 | — | — | |
| SCHEMBL18496422 | 0.74 | — | — | |
| SCHEMBL15616819 | 0.74 | — | — | |
| SCHEMBL15492995 | 0.72 | INPP5A (0.39) | — | |
| SCHEMBL432511 | 0.72 | INPP5A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2650369-B1 | Novel synthetic agonists of TLR9 | IDERA PHARMACEUTICALS INC (US) | 2015-04-29 | — | — | EP | disclosed |